Killing of Pseudomonas aeruginosa by Chicken Cathelicidin-2 Is Immunogenically Silent, Preventing Lung Inflammation In Vivo

The development of antibiotic resistance by Pseudomonas aeruginosa is a major concern in the treatment of bacterial pneumonia. In the search for novel anti-infective therapies, the chicken-derived peptide cathelicidin-2 (CATH-2) has emerged as a potential candidate, with strong broad-spectrum antimi...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Coorens, Maarten, Banaschewski, Brandon J. H., Baer, Brandon J., Yamashita, Cory, van Dijk, Albert, Haagsman, Henk P., Veldhuizen, Ruud A. W., Veldhuizen, Edwin J. A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695126/
https://ncbi.nlm.nih.gov/pubmed/28947647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00546-17
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