Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling

Zinc sequestration by macrophages is considered a crucial host defense strategy against infection by the intracellular bacterium Salmonella enterica serovar Typhimurium. However, the underlying mechanisms remain elusive. In this study, we found that zinc favors pathogen survival within macrophages....

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Wu, Aimin, Tymoszuk, Piotr, Haschka, David, Heeke, Simon, Dichtl, Stefanie, Petzer, Verena, Seifert, Markus, Hilbe, Richard, Sopper, Sieghart, Talasz, Heribert, Bumann, Dirk, Lass-Flörl, Cornelia, Theurl, Igor, Zhang, Keying, Weiss, Guenter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695101/
https://ncbi.nlm.nih.gov/pubmed/28874447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00418-17
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