Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling

Zinc sequestration by macrophages is considered a crucial host defense strategy against infection by the intracellular bacterium Salmonella enterica serovar Typhimurium. However, the underlying mechanisms remain elusive. In this study, we found that zinc favors pathogen survival within macrophages....

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Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Wu, Aimin, Tymoszuk, Piotr, Haschka, David, Heeke, Simon, Dichtl, Stefanie, Petzer, Verena, Seifert, Markus, Hilbe, Richard, Sopper, Sieghart, Talasz, Heribert, Bumann, Dirk, Lass-Flörl, Cornelia, Theurl, Igor, Zhang, Keying, Weiss, Guenter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695101/
https://ncbi.nlm.nih.gov/pubmed/28874447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00418-17
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