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Liposomal (64)Cu-PET Imaging of Anti-VEGF Drug Effects on Liposomal Delivery to Colon Cancer Xenografts

Liposomes (LP) deliver drug to tumors due to enhanced permeability and retention (EPR). LP were labeled with (64)Cu for positron emission tomography (PET) to image tumor localization. Bevacizumab (bev), a VEGF targeted antibody, may modify LP delivery by altering tumor EPR and this change can also b...

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Publicado en:Theranostics
Main Authors: Blocker, Stephanie J., Douglas, Kirk A., Polin, Lisa Anne, Lee, Helen, Hendriks, Bart S., Lalo, Enxhi, Chen, Wei, Shields, Anthony F.
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695009/
https://ncbi.nlm.nih.gov/pubmed/29158822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21688
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