Rhynchophylline Ameliorates Endothelial Dysfunction via Src-PI3K/Akt-eNOS Cascade in the Cultured Intrarenal Arteries of Spontaneous Hypertensive Rats

Objectives: To examine the protective effect of Rhynchophylline (Rhy) on vascular endothelial function in spontaneous hypertensive rats (SHRs) and the underlying mechanism. Methods: Intrarenal arteries of SHRs and Wistar rats were suspended in myograph for force measurement. Expression and phosphory...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Hao, Hui-Feng, Liu, Li-Mei, Pan, Chun-Shui, Wang, Chuan-She, Gao, Yuan-Sheng, Fan, Jing-Yu, Han, Jing-Yan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694770/
https://ncbi.nlm.nih.gov/pubmed/29187825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00928
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