Orexin modulates behavioral fear expression through the locus coeruleus

Emotionally salient information activates orexin neurons in the lateral hypothalamus, leading to increase in sympathetic outflow and vigilance level. How this circuit alters animals’ behavior remains unknown. Here we report that noradrenergic neurons in the locus coeruleus (NA(LC) neurons) projectin...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Soya, Shingo, Takahashi, Tohru M., McHugh, Thomas J., Maejima, Takashi, Herlitze, Stefan, Abe, Manabu, Sakimura, Kenji, Sakurai, Takeshi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694764/
https://ncbi.nlm.nih.gov/pubmed/29151577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01782-z
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