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Polygalae Radix Extract Prevents Axonal Degeneration and Memory Deficits in a Transgenic Mouse Model of Alzheimer’s Disease

Memory impairments in Alzheimer’s disease (AD) occur due to degenerated axons and disrupted neural networks. Since only limited recovery is possible after the destruction of neural networks, preventing axonal degeneration during the early stages of disease progression is necessary to prevent AD. Pol...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Kuboyama, Tomoharu, Hirotsu, Keisuke, Arai, Tetsuya, Yamasaki, Hiroo, Tohda, Chihiro
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694549/
https://ncbi.nlm.nih.gov/pubmed/29184495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00805
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