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Analysis of Nausea in Clinical Studies of Lubiprostone for the Treatment of Constipation Disorders

BACKGROUND: Lubiprostone is a ClC-2 chloride channel activator approved for the treatment of chronic idiopathic constipation (CIC) and opioid-induced constipation (OIC) in adults and irritable bowel syndrome with constipation (IBS-C) in women. Lubiprostone is generally well tolerated, with nausea be...

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發表在:Dig Dis Sci
Main Authors: Cryer, Byron, Drossman, Douglas A., Chey, William D., Webster, Lynn, Habibi, Sepideh, Wang, Martin
格式: Artigo
語言:Inglês
出版: Springer US 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694526/
https://ncbi.nlm.nih.gov/pubmed/28849329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-017-4680-1
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