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Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture

To better understand the roles of microRNAs in glial function, we used a conditional deletion of Dicer1 (Dicer-CKO(MG)) in retinal Müller glia (MG). Dicer1 deletion from the MG leads to an abnormal migration of the cells as early as 1 month after the deletion. By 6 months after Dicer1 deletion, the...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wohl, Stefanie G., Jorstad, Nikolas L., Levine, Edward M., Reh, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693933/
https://ncbi.nlm.nih.gov/pubmed/29150673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01624-y
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