Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity

Oligomannose-type glycans are among the major targets on the gp120 component of the HIV envelope protein (Env) for broadly neutralizing antibodies (bnAbs). However, attempts to elicit oligomannose-specific nAbs by immunizing with natural or synthetic oligomannose have so far not been successful, pos...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Pantophlet, Ralph, Trattnig, Nino, Murrell, Sasha, Lu, Naiomi, Chau, Dennis, Rempel, Caitlin, Wilson, Ian A., Kosma, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693931/
https://ncbi.nlm.nih.gov/pubmed/29150603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01640-y
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