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Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells

Modified mRNA vaccines have developed into an effective and well-tolerated vaccine platform that offers scalable and precise antigen production. Nevertheless, the immunological events leading to strong antibody responses elicited by mRNA vaccines are largely unknown. In this study, we demonstrate th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lindgren, Gustaf, Ols, Sebastian, Liang, Frank, Thompson, Elizabeth A., Lin, Ang, Hellgren, Fredrika, Bahl, Kapil, John, Shinu, Yuzhakov, Olga, Hassett, Kimberly J., Brito, Luis A., Salter, Hugh, Ciaramella, Giuseppe, Loré, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693886/
https://ncbi.nlm.nih.gov/pubmed/29181005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01539
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