In Vitro Maturation and In Vivo Integration and Function of an Engineered Cell-Seeded Disc-like Angle Ply Structure (DAPS) for Total Disc Arthroplasty

Total disc replacement with an engineered substitute is a promising avenue for treating advanced intervertebral disc disease. Toward this goal, we developed cell-seeded disc-like angle ply structures (DAPS) and showed through in vitro studies that these constructs mature to match native disc composi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Martin, J. T., Gullbrand, S. E., Kim, D. H., Ikuta, K., Pfeifer, C. G., Ashinsky, B. G., Smith, L. J., Elliott, D. M., Smith, H. E., Mauck, R. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693867/
https://ncbi.nlm.nih.gov/pubmed/29150639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15887-4
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