Rescue of PFOS-induced human Sertoli cell injury by overexpressing a p-FAK-Y407E phosphomimetic mutant

PFOS induces Sertoli cell injury using testicular cells isolated from rodent testes, but it remains unknown if PFOS has similar effects in humans. Herein, we maintained human Sertoli cells in a mitotically active state in vitro, thus enabling transfection experiments that altered gene expression to...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Chen, Haiqi, Gao, Ying, Mruk, Dolores D., Xiao, Xiang, John, Constance M., Turek, Paul J., Lui, Wing-yee, Lee, Will M., Silvestrini, Bruno, Cheng, C. Yan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693862/
https://ncbi.nlm.nih.gov/pubmed/29150642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15671-4
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