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A primary human lung alveolus-on-a-chip model of intravascular thrombosis for assessment of therapeutics

Pulmonary thrombosis is a significant cause of patient mortality, however, there are no effective in vitro models of thrombi formation in human lung microvessels, that could also assess therapeutics and toxicology of antithrombotic drugs. Here we show that a microfluidic lung alveolus-on-a-chip line...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Jain, Abhishek, Barrile, Riccardo, van der Meer, Andries D., Mammoto, Akiko, Mammoto, Tadanori, De Ceunynck, Karen, Aisiku, Omozuanvbo, Otieno, Monicah A., Louden, Calvert S., Hamilton, Geraldine A., Flaumenhaft, Robert, Ingber, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693794/
https://ncbi.nlm.nih.gov/pubmed/28516446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.742
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