The Hypercoagulability Paradox of Chronic Kidney Disease: The Role of Fibrinogen

BACKGROUND: Chronic kidney disease (CKD) patients have increased rates of bleeding as well as thrombosis. Fibrinogen and platelets combine to generate a mature clot, but in CKD platelets are dysfunctional. Therefore, we hypothesize that CKD patients have increased clot strength due to elevated fibri...

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Detalhes bibliográficos
Publicado no:Am J Surg
Main Authors: Nunns, Geoffrey R, Moore, Ernest E, Chapman, Michael P, Moore, Hunter B, Stettler, Gregory R, Peltz, Erik, Burlew, Clay C, Silliman, Christopher C, Banerjee, Anirban, Sauaia, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693753/
https://ncbi.nlm.nih.gov/pubmed/28951066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2017.08.039
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