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Small Airway Absorption and Microdosimetry of Inhaled Corticosteroid Particles after Deposition
PURPOSE: To predict the cellular-level epithelial absorbed dose from deposited inhaled corticosteroid (ICS) particles in a model of an expanding and contracting small airway segment for different particle forms. METHODS: A computational fluid dynamics (CFD)-based model of drug dissolution, absorptio...
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| 出版年: | Pharm Res |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693636/ https://ncbi.nlm.nih.gov/pubmed/28643237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2210-7 |
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