Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice

Carbonic anhydrase-8 (Car8 mouse gene symbol) is devoid of enzymatic activity, but instead functions as an allosteric inhibitor of inositol trisphosphate receptor-1 (ITPR1) to regulate this intracellular calcium release channel important in synaptic functions and neuronal excitability. Causative mut...

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Detalhes bibliográficos
Publicado no:Mamm Genome
Main Authors: Levitt, Roy C., Zhuang, Gerald Y., Kang, Yuan, Erasso, Diana M., Upadhyay, Udita, Ozdemir, Mehtap, Fu, Eugene S., Sarantopoulos, Konstantinos D., Smith, Shad B., Maixner, William, Diatchenko, Luda, Martin, Eden R., Wiltshire, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693610/
https://ncbi.nlm.nih.gov/pubmed/28547032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-017-9694-7
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