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Effect of a rare genetic variant of TM7SF4 gene on osteoclasts of patients with Paget’s disease of bone
BACKGROUND: Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) is involved in osteoclastogenesis with a key role in mononucleated osteoclasts fusion. We reported in patients with Paget’s disease of bone (PDB) a rare variant (rs62620995) in the TM7SF4 gene, encoding for DC-STAMP, which changes...
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| Pubblicato in: | BMC Med Genet |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693359/ https://ncbi.nlm.nih.gov/pubmed/29145829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-017-0495-3 |
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