The trehalose-specific transporter LpqY-SugABC is required for antimicrobial and anti-biofilm activity of trehalose analogues in Mycobacterium smegmatis

Mycobacteria, including the bacterial pathogen that causes human tuberculosis, possess distinctive pathways for synthesizing and utilizing the non-mammalian disaccharide trehalose. Trehalose metabolism is essential for mycobacterial viability and has been linked to in vitro biofilm formation, which...

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Bibliographic Details
Published in:Carbohydr Res
Main Authors: Wolber, Jeffrey M., Urbanek, Bailey L., Meints, Lisa M., Piligian, Brent F., Lopez-Casillas, Irene C., Zochowski, Kailey M., Woodruff, Peter J., Swarts, Benjamin M.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693249/
https://ncbi.nlm.nih.gov/pubmed/28917089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2017.08.003
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