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EXTH-20. ENHANCEMENT OF GAP JUNCTIONAL ACTIVITY BY iPS CELL-DERIVED NEURAL STEM CELLS IN STEM CELL-BASED SUICIDE GENE THERAPY

BACKGROUND: Stem cell-based suicide gene therapy is a feasible treatment strategy for malignant brain tumors. The Mechanism includes several steps; (1) intratumorally implanted effector cells transduced with herpes simplex virus-thymidine kinase (HSVtk) gene migrate to the tumor site and form gap ju...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Kenmochi, Hiroaki, Yamasaki, Tomohiro, Namba, Hiroki
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693202/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.315
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