IMMU-30. TCR Vb CLONAL EXPANSION PREDICTS RESPONSE TO ADOPTIVE IMMUNOTHERAPY AGAINST MEDULLOBLASTOMA

BACKGROUD: Adoptive cell therapy has led to robust overall response rates in patients with metastatic disease. In patients with durable responses after adoptive immunotherapy, sequencing of TCR Vβ demonstrated multiple T cell clonotypes in the adoptively transferred cells, but showed clonotypic expa...

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Опубликовано в: :Neuro Oncol
Главные авторы: Flores, Catherine, Wildes, Tyler, Pham, Christina, Abraham, Rebecca, Mooree, Ginger, Mitchell, Duane
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693149/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.488
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