SCDT-42. ENHANCED IN VIVO EFFICACY AND SAFETY OF COMBINATION TEMOZOLOMIDE AND BROMODOMAIN INHIBITOR THERAPY FOR GLIOMAS USING A TARGETED DUAL DRUG-LOADING STEALTH LIPOSOMAL CARRIER

Effective treatment for gliomablastoma (GBM) is limited by the presence of the blood-brain barrier (BBB) and rapid resistance to single agent therapies. To address these issues, we developed a transferrin functionalized nanoparticle (Tf-NP) that can deliver dual combination therapies. Using intravit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Lam, Fred C, Morton, Stephen W, Wyckoff, Jeffrey, Maffa, Amanda, Balkanska-Sinclair, Elena, Floyd, Scott R, Yaffe, Michael B, Hammond, Paula T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693072/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1122
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados