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TMOD-19. SOMATIC GENOME EDITING WITH THE RCAS-CRISPR/Cas9 SYSTEM FOR PRECISION GLIOMA MODELING

It has been gradually established that the vast majority of human tumors are extraordinarily heterogeneous at a genetic level. To accurately recapitulate this complexity, it is now evident that in vivo animal models of cancers will require to recreate not just a handful of simple genetic alterations...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: García, Álvaro Curiel, Oldrini, Barbara, Marques, Carolina, Matia, Veronica, Squatrito, Massimo
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693047/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1056
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