IMMU-20. CHARACTERIZING THE IMMUNE LANDSCAPE OF PD-1/PD-L1 IN BRAIN TUMOR IMMUNE CELL POPULATION USING CyTOF MASS CyTOMETRY

INTRODUCTION: Immunotherapy may be a viable and efficacious treatment strategy for glioblastoma and other brain tumors. However, the negative co-stimulatory molecule PD-1 and its ligand PD-L1, which contributes to T cell inhibition in the tumor context, may limit effective anti-tumor immune response...

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Vydáno v:Neuro Oncol
Hlavní autoři: Lee, Alexander, Davidson, Tom, Galvez, Mildred, Nathanson, David, Wang, Anthony, Liau, Linda, Prins, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5693003/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.478
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