ACTR-25. PHASE I/II STUDY OF TEMOZOLOMIDE PLUS NIMUSTINE CHEMOTHERAPY FOR RECURRENT MALIGNANT GLIOMAS: KYOTO NEURO-ONCOLOGY GROUP

The objective of this phase I/II study was to examine the efficacy and toxicity profile of temozolomide (TMZ) plus nimustine (ACNU). Patients who had received a standard radiotherapy with one or two previous chemo-regimens were enrolled. In phase I, the maximum-tolerated dose (MTD) by TMZ (150 mg/m2...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Aoki, Tomokazu, Arakawa, Yoshiki, Ueba, Tetsuya, Oda, Masashi, Nishida, Namiko, Akiyama, Yukinori, Tsukahara, Tetsuya, Mikuni, Nobuhiro, Miyamoto, Susumu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692951/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.020
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