TMIC-25. TUMOR MIGRATION AND ROLE OF MICROENVIRONMENT IN DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is a fatal pediatric brain cancer which presents an immense therapeutic challenge. Our previous work has shown that histone mutations (H3K27M) arise in the pontine tumor but in most cases necessitates an obligate partner mutation for tumorigenesis and spread....

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Vydáno v:Neuro Oncol
Hlavní autoři: Kambhampati, Madhuri, Panditharatna, Eshini, Yadavilli, Sridevi, Ho, Cheng-Ying, Kilburn, Lindsay, Hwang, Eugene, Rood, Brian, Bornhorst, Miriam, Magge, Suresh, Gittens, Jamila, Clark, Madeline, Packer, Roger, Nazarian, Javad
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692934/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1014
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