PATH-35. MAINTENANCE OF EGFR ABNORMALITIES OVER TIME AND COMPARISON OF MOLECULAR METHODOLOGIES IN GLIOBLASTOMA (GBM)

BACKGROUND: There is controversy surrounding the frequency with which EGFR abnormalities are maintained as therapeutic targets in serial GBM samples. In addition, there are multiple methods used to detect EGFRamp and EGFRvIII. Finally, a recent analysis suggested EGFR amp may be less common in GBMs...

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Vydáno v:Neuro Oncol
Hlavní autoři: Lassman, Andrew, Dimino, Cara, Mansukhani, Mahesh, Murty, Vundavalli, Holen, Kyle D, Ansell, Peter J, Canoll, Peter, Butowski, Nicholas, Phillips, Joanna J, Yong, William, Cloughesy, Timothy
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692845/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.725
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