STEM-42. GENOME-WIDE CRISPR SCREENS IN BRAIN TUMOR INITIATING CELLS (BTICS) IDENTIFY POTENT SENSITIZERS OF CONVENTIONAL CHEMORADIOTHERAPY

Glioblastoma (GBM) is a highly aggressive and most common form of malignant primary brain tumor in adults (WHO grade IV). Despite surgical and adjuvant therapeutic interventions, including chemotherapy with the alkylating agent TMZ and cranial irradiation, GBM relapse is inevitable with a median sur...

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Publicado no:Neuro Oncol
Main Authors: Chokshi, Chirayu, Tieu, David, Vora, Parvez, Venugopal, Chitra, Chan, Katherine, Tong, Amy, Brown, Kevin, Singh, Mohini, Moffat, Jason, Singh, Sheila
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692777/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.956
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