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ACTR-52. CLINICAL IMPACT OF TERT PROMOTER DETECTION IN CIRCULATING CELL-FREE DNA OF PATIENTS WITH GLIOBLASTOMA – A PILOT STUDY

BACKGROUND: Detection of circulating cell-free tumor-derived DNA (cfDNA) has been shown to be of clinical value in monitoring cancer treatment. Having in mind that somatic TERT promoter (TERTp) mutations are clonal and frequent in IDH-wild-type glioblastoma (GBM), we conducted a pilot study to asses...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Juratli, Tareq, Stasik, Sebastian, Richter, Sven, Zolal, Amir, Schackert, Gabriele, Krex, Dietmar, Thiede, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692736/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.043
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