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TMIC-20. INHIBITION OF SLC7A11 REDUCES EXCITATORY SYNAPTIC INPUT OF PERITUMORAL NEURONS IN GLIOMA PATIENTS

INTRODUCTION: Malignant glioma is frequently associated with drug-resistant epilepsy which limits quality-of-life. Expression of SLC7A11, a cysteine-glutamate antiporter, in gliomas has been shown to be associated with poor survival and an increased rate of glioma induced epilepsy. However, the medi...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Sauvigny, Thomas, Dührsen, Lasse, Kuhl, Dietmar, Westphal, Manfred, Ohana, Ora, Martens, Tobias
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692735/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1010
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