CSIG-04. WNT SIGNALING REGULATES ALDEHYDE DEHYDROGENASE 3A1 (ALDH3A1) TO INDUCE TEMOZOLOMIDE RESISTANCE IN GLIOBLASTOMA CELLS

Glioma stem cells (GSCs) are considered to be responsible for glioblastoma’s dismal prognosis. The Wingless (WNT) signaling pathway promotes stemness and resistance towards chemo- and radiotherapy in glioblastoma. We have previously shown that pharmacological WNT inhibition using the porcupine inhib...

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Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Suwala, Abigail K, Koch, Katharina, Deenen, Rene, Köhrer, Karl, Felsberg, Jörg, Reifenberger, Guido, Kahlert, Ulf, Maciaczyk, Jaroslaw
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
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Abstracts
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692671/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.199
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