CBIO-08. DIRECTED NEURONAL DIFFERENTIATION IN GBM BY SUPPRESSION OF TAZ

IDH-mutant (IDH-MUT) glioma patients show highly improved prognosis compared to those with wild-type IDH. However, IDH mutations are rare in the more aggressive grade IV glioblastomas and introducing IDH mutations in mouse neural cells does not induce gliomagenesis. This is a paradox, given that IDH...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Audia, Alessandra, Das, Arvid, Mukheef, Farah, Zhang, Ze-yan, Sulman, Erik, Bhat, Krishna
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692618/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.130
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