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CBIO-08. DIRECTED NEURONAL DIFFERENTIATION IN GBM BY SUPPRESSION OF TAZ
IDH-mutant (IDH-MUT) glioma patients show highly improved prognosis compared to those with wild-type IDH. However, IDH mutations are rare in the more aggressive grade IV glioblastomas and introducing IDH mutations in mouse neural cells does not induce gliomagenesis. This is a paradox, given that IDH...
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| Publicat a: | Neuro Oncol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692618/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.130 |
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