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GPCRs globally coevolved with receptor activity-modifying proteins, RAMPs
Receptor activity-modifying proteins (RAMPs) are widely expressed in human tissues and, in some cases, have been shown to affect surface expression or ligand specificity of G-protein–coupled receptors (GPCRs). However, whether RAMP−GPCR interactions are widespread, and the nature of their functional...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692586/ https://ncbi.nlm.nih.gov/pubmed/29078385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713074114 |
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