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RARE-09. MINIMALLY TOXIC MULTIMODAL AND POLYPHARMACOLOGICAL THERAPY IN TREATMENT OF DIFFUSE MIDLINE GLIOMA

INTRODUCTION: Malignant gliomas are among the most deadly human cancers. One subtype, diffuse midline glioma (DMG), WHO Grade IV, is characterized by the H3 K27M histone mutation which is mutually exclusive with the favorable MGMT promoter methylation, IDH 1/2 mutation and EGFR amplification. DMGs h...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Salacz, Michael, Halatsch, Marc-Eric, Karpel-Massler, Georg, Kast, Richard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692515/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.862
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