STEM-31. TARGETING GLIOBLASTOMA STEM CELLS BY PERTURBING A NOVEL GENE REGULATORY CLUSTER TO REDUCE TUMOR RECURRENCE

Glioblastoma (GBM) is the most prevalent and aggressive brain cancer in adults. GBM is enriched with glioma stem-like cells (GSCs) that contribute to tumor initiation and treatment resistance and thus a natural focus for therapeutic development. However, targeting GSCs has been a challenge because o...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Deng, Changwang, Sebastian, Mathew, Le, Son, Chen, Dongjiang, Thomas, Nagheme, Tran, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692499/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.946
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