RARE-35. DABRAFENIB IN PATIENTS WITH RECURRENT, BRAF V600E MUTATED MALIGNANT GLIOMA AND LEPTOMENINGEAL DISEASE

BRAF V600E mutations occur frequently in malignant melanoma but are rare in most glioma subtypes. Besides more benign brain tumors, like ganglioglioma, dysembryoblastic neuroepithelial tumours and supratentorial pilocytic astrocytomas, only pleomorphic xanthoastrocytomas (50-78%) and epitheloid glio...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Burger, Michael, Ronellenfitsch, Michael, Lorenz, Nadja, Wagner, Marlies, Voss, Martin, Capper, David, Tzaridis, Theophilos, Herrlinger, Ulrich, Steinbach, Joachim, Stoffels, Gabriele, Langen, Karl-Josef, Brandts, Christian, Senft, Christian, Harter, Patrick, Baehr, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692495/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.877
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