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SCDT-41. IN VIVO TESTING OF INTRACRANIAL DELIVERY OF RECOMBINANT HUMAN IL-12 AND IL-12Fc AND FUNCTIONAL ASSESSMENT ON HUMAN, PORCINE AND CANINE PERIPHERAL BLOOD MONONUCLEAR CELLS

Brain cancers are known to form a highly immunosuppressive microenvironment, suggesting that patients could benefit from immunomodulatory drugs. Moreover, the brain is per se an immunologically unique site with reduced cellular infiltration and antigen presentation. Multiple therapies focusing on lo...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Beffinger, Michal, Schellhammer, Linda, Pantelyushin, Stanislav, Wall, Samantha K, Bienemann, Ali, Granger, Nicolas, Buch, Thorsten, vom Berg, Johannes
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692477/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1121
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