IMMU-39. COMBINATION OF RADIOTHERAPY WITH A 4-1BB AGONIST ANTIBODY AND A TIM-3 APTAMER RESULTS IN ENHANCED SURVIVAL IN A DIPG MODEL

Diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric tumors. Despite advances in targeted treatments radiotherapy remains as the standard treatment being just palliative. The lack of effective therapies represents a critical unmet need for many pediatric solid tumors. Cancer immunother...

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Vydáno v:Neuro Oncol
Hlavní autoři: Martínez-Vélez, Naiara, Sanchez, Miguel Marigil, Puigdelloses, Monsterrat, Garcia-Moure, Marc, Aristu, Jose Javier, Dominguez, Pablo, Rico, Mikel, Becher, Oren, Ramos, Luis, Pastor, Fernando, Valle, Ricardo Diez, Tejada, Sonia, Alonso, Marta M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692351/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.497
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