ATIM-19. POPULATION PHARMACOKINETIC (PPK) ANALYSIS OF NIVOLUMAB FLAT AND WEIGHT-BASED DOSING REGIMENS AND ASSOCIATIONS WITH SAFETY IN PATIENTS WITH RECURRENT GLIOBLASTOMA (rGBM) TREATED IN CHECKMATE 143

BACKGROUND: Nivolumab 3 mg/kg Q2W was well tolerated in rGBM in CheckMate 143 (NCT02017717). It is unknown if nivolumab PK will differ in rGBM vs other tumor types; therefore, a PPK analysis was performed to compare nivolumab PK in patients with rGBM vs those with NSCLC. Additionally, this analysis...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Shen, Jun, Hruska, Matthew, Zwirtes, Ricardo, Potter, Von, Paliwal, Prashni, Roy, Amit, Bello, Akintunde, Suryawanshi, Satyendra, Lim, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692350/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.114
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