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PATH-05. ALDH1A3, THE CRITICAL ALDEHYDE DEHYDROGENASE ISOFORM, DETERMINES GLIOMA STEM-LIKE CELL MESENCHYMAL IDENTITY AND POOR CLINICAL OUTCOME
BACKGROUND: Mesenchymal (MES) transdifferentiation in glioma stem cells (GSCs) is associated with advanced malignancy and poor outcome in glioblastoma (GBM) patients. Identification of key regulator is therefore critical for developing GSCs-targeted therapy. Aldehyde dehydrogenase (ALDH) is thought...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692336/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.696 |
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