ACTR-37. PREDICTIVE SIGNIFICANCE OF IDH1/2 MUTATION AND 1p/19q CO-DELETION STATUS IN A POST-HOC ANALYSIS OF NRG ONCOLOGY/RTOG 9802: A PHASE III TRIAL OF RT VS RT + PCV IN HIGH RISK LOW-GRADE GLIOMAS

BACKGROUND: This study investigated the predictive significance of IDH1/2 mutations and 1p/19q co-deletion in patients with high risk (age≥40 or subtotal resection/biopsy) low-grade gliomas (LGGs), randomized to receive RT with or without PCV after biopsy/surgical resection in NRG Oncology/RTOG 9802...

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Publicado no:Neuro Oncol
Main Authors: Bell, Erica H, Zhang, Peixin, Shaw, Edward G, Buckner, Jan C, Barger, Geoffrey R, Coons, Stephen W, Bullard, Dennis E, Mehta, Minesh P, Gilbert, Mark R, Brown, Paul D, Stelzer, Keith J, Fleming, Jessica, McElroy, Joseph P, Timmers, Cynthia D, Becker, Aline Paixao, Salavaggione, Andrea L, Liu, Ziyan, Aldape, Ken, Brachman, David G, Gertler, Stanley Z, Murtha, Albert D, Schultz, Christopher J, Johnson, David, Shu, Hui-Kuo, Chakravarti, Arnab
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692306/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.028
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