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ACTR-18. INTERFERON-ALPHA ENHANCES TEMOZOLOMIDE ANTI-GLIOMA EFFICACY: FROM BENCH TO BEDSIDE

BACKGROUND: O6-methylguanine DNA methyltranferase (MGMT) is one of the main mechanisms of chemoresistance for alkylating agents in malignant gliomas. Treatment for MGMT positive glioma is still challenge in clinical practice. METHODS: We firstly tested anti-tumor efficacy of IFN-α combined with temo...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Chen, Zhong-ping, Yang, Qunying, Guo, Chengcheng, Shen, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692094/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.013
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