TMOD-16. MODELING GLIOBLASTOMA THROUGH CANCER STEM CELL ORGANOIDS

Glioblastoma (GBM) therapeutic resistance is driven in part by tumor-initiating, cancer stem cells (CSCs) which rely on complex interactions with the tumor microenvironment. Standard cell culture conditions fail to recapitulate the original tumor architecture or microenvironmental gradients, and are...

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Pubblicato in:Neuro Oncol
Autori principali: Hubert, Christopher, Rivera, Maricruz, Wallace, Lisa C, Wu, Qiulian, Mack, Stephen, Prager, Briana, Miller, Tyler E, Couce, Marta, McLendon, Roger, Sloan, Andrew, Rich, Jeremy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692089/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1054
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