EXTH-16. RATIONAL DESIGN OF COMBINATION THERAPY AGAINST HER2+ BRAIN METASTASES OF BREAST CANCER USING JQ-1 AND VINORELBINE

Brain metastasis is a late complication of breast cancer progression and portends poor survival, in part due to an absence of targeted therapies. Our previous work established βIII-tubulin as a novel therapeutic target for brain metastases of breast cancer. Beta III-tubulin is a protein expressed pr...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Panek, Wojciech K, Kanojia, Deepak, Xiao, Annie, Lesniak, Maciej S
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692064/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.311
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