IMMU-66. IDO1 EXPRESSION STRATIFIES PATIENT SURVIVAL AND IS REGULATED BY TUMOR INFILTRATING T CELLS IN HUMAN GLIOBLASTOMA

PURPOSE: Indoleamine 2, 3 dioxygenase 1 (IDO1) mediates potent immunosuppression in multiple preclinical models of cancer. However, the basis for elevated IDO1 expression in human cancer, including the most common and malignant primary brain tumor in adults, glioblastoma (GBM), is poorly understood....

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Zhai, Lijie, Ladomersky, Erik, Lauing, Kristen, Wu, Meijing, Genet, Matthew, Gritsina, Galina, Gyorffy, Balazs, Brastianos, Priscilla, Binder, David, Sosman, Jeffrey, Giles, Francis, James, C David, Horbinski, Craig M, Stupp, Roger, Wainwright, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691987/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.523
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