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CSIG-21. IDH3 PROMOTES GLIOBLASTOMA GROWTH THROUGH REGULATION OF ONE CARBON METABOLISM
Neomorphic mutations in isocitrate dehydrogenase (IDH)1 and IDH2, but not in IDH3, have been identified in acute myelogenous leukemia, low-grade glioma, and secondary glioblastoma. In addition, as shown recently by our group, non-mutated wild-type IDH1 mRNA and protein are commonly overexpressed in...
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| Publicado en: | Neuro Oncol |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5691983/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.215 |
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