RARE-22. SINGLE-AGENT DABRAFENIB FOR INTRACRANIAL BRAF(V600E)-MUTATED HISTIOCYTOSIS

Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), and a mixed ECD/LCH phenotype are histiocytic neoplasms harboring BRAFV600E mutations in half or more cases. Intracranial manifestations of these diseases are refractory to conventional treatments and associated with morbidity and m...

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Publicat a:Neuro Oncol
Autors principals: Bhatia, Ankush, Ulaner, Gary, Rampal, Raajit, Hyman, David, Abdel-Wahab, Omar, Durham, Benjamin, Hajdenberg, Julio, Ganzel, Chezi, Diamond, Eli
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691982/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.869
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