Network pharmacological mechanisms of Vernonia anthelmintica (L.) in the treatment of vitiligo: Isorhamnetin induction of melanogenesis via up-regulation of melanin-biosynthetic genes

BACKGROUND: Vitiligo is a long-term skin disease characterized by the loss of pigment in the skin. The current therapeutic approaches are limited. Although the anti-vitiligo mechanisms of Vernonia anthelmintica (L.) remain ambiguous, the herb has been broadly used in Uyghur hospitals to treat vitili...

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Publicat a:BMC Syst Biol
Autors principals: Wang, Ji Ye, Chen, Hong, Wang, Yin Yin, Wang, Xiao Qin, Chen, Han Ying, Zhang, Mei, Tang, Yun, Zhang, Bo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691595/
https://ncbi.nlm.nih.gov/pubmed/29145845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0486-1
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