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Synthesis, characterization, cytotoxic screening, and density functional theory studies of new derivatives of quinazolin-4(3H)-one Schiff bases

A series of novel derivatives of quinazolinone Schiff bases were synthesized from benzoic acid starting material and evaluated for potential cytotoxic activities against the human breast adenocarcinoma (MCF-7) and the human colon adenocarcinoma (HT-29) cell lines. Compared to the reference drug, the...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Nasab, Rezvan Rezaee, Hassanzadeh, Farshid, Khodarahmi, Ghadam Ali, Mirzaei, Mahmoud, Rostami, Mahboubeh, abadi, Ali Jahanian-Najaf
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691571/
https://ncbi.nlm.nih.gov/pubmed/29204173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.217425
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