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Blocking CCR7 at the Ocular Surface Impairs the Pathogenic Contribution of Dendritic Cells in Allergic Conjunctivitis

CCR7 plays a key role in mobilizing tissue dendritic cells (DCs) to the lymphoid compartment for consequent elicitation of adaptive immunity. Interfering with CCR7 function therapeutically would therefore be anticipated to inhibit the progression of atopic conditions, for example, allergic conjuncti...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Schlereth, Simona, Lee, Hyun Soo, Khandelwal, Payal, Saban, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691338/
https://ncbi.nlm.nih.gov/pubmed/22507838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.02.015
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