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Dose de-escalation to the normal larynx using conformal radiotherapy reduces toxicity while maintaining oncologic outcome for T1/T2 glottic cancer

We evaluated the efficacy of dose de-escalation to the normal larynx using conformal radiotherapy (CRT) for T1/T2 glottic cancer. For conventional RT (2DRT, n = 38), the laryngeal box received a median equivalent dose in 2 Gy fractions (EQD2) of 66 Gy. For CRT (n = 42; 3D-CRT, 20; intensity-modulate...

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Publicat a:Sci Rep
Autors principals: Kim, Jun Won, Byeon, Hyung Kwon, Choi, Hong-Shik, Lee, Ik Jae
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691141/
https://ncbi.nlm.nih.gov/pubmed/29147004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15974-6
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